St. Petersburg, FL January 29, 2007, Life Sciences, Inc. announces the commercial availability of a selection of Dye-Doped Silica Nanoparticles (DDSNP) for use as reporters in improved bioanalytic systems. Each nanoparticle encapsulates thousands of dye molecules, producing extremely bright fluorescence for greater sensitivity.

The DDSNP are available with a variety of fluorophores and offer a 300 to 1,000 fold increase in emitted light as compared with an individual molecule of fluorescent dye. Available dyes include fluorescein, HEX, ROX, RuBpy and TAMRA. Custom particles can be synthesized in sizes ranging from 20 - 100 nm in diameter. In addition, nanoparticles with customized Stoke’s shift offer an opportunity for assay and instrument developers to specify desired excitation and emission wavelengths for their systems.

Biomolecules can be conjugated to DDSNP through chemical binding, or covalent coupling. The particles can be surface functionalized with thiol (-SH), cyanate ester (-OCN), amino (-NH2) or carboxyl (-COOH) groups. Further surface modification can immobilize biotin, DNA, antibodies, enzymes, and other proteins on the nanoparticles.

Dye-Doped Silica Nanoparticles are available from Life Sciences, Inc. in research or production quantities. For more information or to purchase, visit our product catalog.

View LSI Nanoparticle Information Page

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Prefabricated Gene-Lab Provides Controlled Workflow and Reduced Cross Contamination

St. Petersburg, FL September 20, 2006, Life Sciences, Inc. announces Gene-Lab, a new prefabricated laboratory for PCR and NASBA nucleic acid amplification assays. Gene-Lab provides the segregated, controlled work environment required to minimize cross-contamination and is intended as a renovation for existing laboratories or as part of a larger new construction project. This product eliminates the expense and time delay associated with developing a custom lab design.

The design features 3 work rooms, each with a dedicate vestibule. The lab includes lighting, wiring for 120 VAC power, telephone and ethernet, a hands-free sink and plumbing, work surfaces, electronically controlled transfer airlocks and a controlled airflow system. Rooms are sealed to prevent airflow between work areas. Construction features hard surface counter and walls that are readily washable for contamination control. The airflow system provides independent control for each room from a central panel that also incorporates power control.

Gene-Lab requires an installation space approximately 16 by 20 feet with a 10 foot ceiling. Installation in North American facilities is by Life Sciences, Inc., exclusive North American distributor for the manufacturer, Bioer Technology Co. For more information, please visit our website www.LifeSci.com.

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Molecular Biology Grade Trehalose Dihydrate is Negative for Nucleases and Endotoxins

St. Petersburg, FL July 20, 2006, Life Sciences, Inc. announces a new high Purity grade of trehalose dihydrate suitable for protein and cell stabilization. Trehalose Dihydrate M.B. has a very low bioburden and each lot is tested negative for RNase, DNase and endotoxins. Specification for colony-forming units is less than 25 per gram.

Trehalose is well documented in scientific literature for properties that stabilize proteins and cells under stress from dehydration, heat and cold.  This non-reducing sugar is apparently superior to many other stabilizers both for its broad effectiveness as a stabilizer and for its minimal chemical interaction.

Trehalose Dihydrate M.B. is a white crystalline powder of greater than 99.0% purity. It is available from Life Sciences, Inc. in small or large quantity. For more information, contact us.

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Download the PDF Data Sheet on Trehalose